Specialist officers acting on intelligence discovered the "large-scale" cultivation on Swanston Street, Glasgow, on Friday.
Three South East Asian men, believed to be Vietnamese and possible human trafficking victims, were found at the premises.
The drugs and the cannabis farm are thought to be linked and two men aged 41 and 34 have been arrested.
They are expected to appear at Glasgow Sheriff Court on Monday.
"Criminal behaviour like this spreads harm and misery and we are committed to detecting and disrupting those intent on bringing drugs to Glasgow and enforcing that this type of behaviour will not be tolerated."
"I would also like to reassure the public that the three men, believed to be potential victims of human trafficking, are being provided with support and advice while enquires are carried out."