Norwich manager Dean Smith revealed there is “concern” for his captain ahead of Saturday’s visit of West Brom after the Scotland centre-back picked up a shoulder injury following the 3-2 win over Bristol City in midweek.
Hanley has helped Norwich to six straight league wins in the English Championship and his absence would be a blow for both club and country.
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Hide AdScotland head coach Steve Clarke is already without a number of injured defenders after captain Andy Robertson, and centre-back duo Liam Cooper and John Souttar, all failed to make the squad.
Hanley’s potential withdrawal would leave only four recognised centre-halves for Clarke to choose from – namely Scott McKenna, Jack Hendry, Ryan Porteous and Kieran Tierney – ahead of three matches in the space of six days.
Scotland face Ukraine home and away either side of hosting Ireland next Saturday.