And those MPs will include the Prime Minister himself, with Boris Johnson holding a majority of only 5,034 votes in his own constituency of Uxbridge and South Ruislip.
No incumbent Prime Minister has ever lost their seat at a UK general election, but what if Mr Johnson was to become the first?
Uxbridge and South Ruislip is a constituency with an electorate of around 72,000 people in Greater London.
The constituency was created in 2010 and has ever-since elected a Conservative, including Mr Johnson since 2015, before which he was Mayor of London.
It remains possible for Mr Johnson to remain Prime Minister even if he were to lose his seat.
However, while there is nothing in the constitution that says a member of the government has to be an MP, Mr Johnson would face extraordinary pressure to step down as UK leader if he were to lose his seat.
Brunel University London sits in Mr Johnson's constituency and could see large numbers of students trying to oust him.
His main opponent, Labour's Ali Reza Milani was also a graduate of Brunel University and is a former President of the Union of Brunel Students, which could help him in his quest to defeat the incumbent PM.
Johnson's Uxbridge and South Ruislip seat is expected to be declared around 4:30am.