In that time, the current affairs panel show has played an important role in giving young comedy talent a platform, from which many have gone on to become household names.
As its time on BBC Two comes to an end, we look at some of the big name stand-ups who have emerged from the series.
5. Andy Parsons
Andy Parsons was another early favourite for fans of the show. He had previously honed his comedy skills writing for the legendary Spitting Image. Photo: Contributed
6. James Acaster
James Acaster arrived on the show a relative unknown, but after raising his profile on the Mock the Week, and he went on to star in his own serialised Netflix stand-up comedy special, Repertoire. Photo: Contributed
7. Romesh Ranganathan
After appearing on Mock the Week, Romesh went on to become a household name, with shows such as The Ranganation and Just Another Immigrant, and was a regular on A League Of Their Own. Photo: Contributed
8. Rob Beckett
The London comic's appearances on MTW won him over legions of fans, and he continued to work with Ramesh Ranganathan as the pair explored the world on camera and highlighted the absurdities of life. Photo: Contributed