Among the 20 stars hoping to impress with their baking skills are Scottish actor James McAvoy, Little Mix’s Jade Thirlwall and comedian John Bishop.
Also appearing are rapper Dizzee Rascal, Star Wars actress Daisy Ridley, TV presenter Stacey Dooley, double Olympic champion Dame Kelly Holmes, comedian and presenter Tom Allen, and author and TV star David Baddiel.
The list of celebrity participants also includes YouTuber and musician KSI, Paralympian Ade Adepitan, author and psychotherapist Philippa Perry, radio DJ Nick Grimshaw and comedian Rob Beckett.
Former X Factor winner Alexandra Burke, TV star Anneka Rice, actor Reece Shearsmith, singers Anne-Marie and Nadine Coyle, and comedian Katherine Ryan are also all on board.
Each episode will see four celebrities battle it out over three rounds – the Signature, the Technical and the Showstopper – in a bid to be crowned Star Baker.
Prue Leith and Paul Hollywood will be judging the bakes while host Matt Lucas will also return to the tent “keeping time and spirits up”.
Across five episodes, due to air in the spring, the celebrities will be doing their bit in aid of Stand Up To Cancer, a joint national fundraising campaign from Cancer Research UK and Channel 4.
Sarah Lazenby, head of formats and features at Channel 4, said: “What we all need right now is more joy. Bake Off is serving up yet another dollop of fun courtesy of some very willing celebrities.
“We can’t promise a huge helping of baking inspiration, but we can deliver some much-needed laughs.”
Kieran Smith, executive producer of Bake Off creators Love Productions, said: “Bake Off is extremely proud to support Stand Up To Cancer.
“It has been a difficult year for charities and we sincerely hope that this series will offer a lot of fun, but also some much-needed funds in the fight against cancer.”
Stand Up To Cancer has raised more than £62 million, funding 55 clinical trials and projects involving 11,000 cancer patients across the country, Channel 4 said.