The Scottish Fire and Rescue Service have confirmed they are in attendance at an incident on George IV Bridge in the centre of Edinburgh.
They have labelled it a level four fire and have been on site since early Tuesday morning.
One person has been taken to hospital due to the incident and many residents have been evacuated from their homes in the area.
A Scottish Fire and Rescue Service spokesperson said: “We were alerted at 6.18 am on Tuesday, August 24 to reports of a building on fire at George IV Bridge, Edinburgh.
“Operations Control mobilised nine appliances and two height vehicles to the scene where firefighters are tackling a fire affecting a number of properties.
“Crews are still in attendance.”
It is not clear where the fire started, but there are reports of extreme fire and water damage to several businesses including wall collapse next to the Elephant House Cafe.