Tennis: Federer bites the dust in Miami
The world No.1 committed 62 unforced errors and was broken three times as Berdych of the Czech Republic fought through in just under three hours, ending an eight-match losing streak against the Swiss star.
The 16th seed saved eight of ten break points – with seven of those coming in a tense second set – on his way to the quarter-finals and a clash with Fernando Verdasco.
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Hide AdRafael Nadal was made to suffer before triumphing 7-6(7/5), 6-4 over compatriot David Ferrer in a gritty affair full of unforced errors.
The Spaniard will face eighth seed Jo-Wilfried Tsonga after he dismantled former world No.1 Juan Carlos Ferrero 6-2, 6-2.
Andy Roddick will face Spain's Nicolas Almagro in the last eight after recovering from an awful start to beat Germany's Benjamin Becker.