The 48-year-old former Open champion has won of a total of eight European Tour titles. He has also played in two Ryder Cups and has also been a vice-captain once.
Lawrie continues to compete at the sharp end of the world game and won the Dimension Data Pro-Am on the Sunshine Tour on Sunday.
He also plays a significant role in Scottish grassroots golf through the Paul Lawrie Foundation and hosts the Saltire Energy Paul Lawrie Match Play tournament for a third time this year.
Paul said: “I’ve known Chubby Chandler ever since I’ve been out on Tour and it will be great to be working with him and the guys at ISM.
“I’m coming into an interesting phase in my career. I’m convinced I’ve got a lot of good golf ahead of me and I’m looking forward to some exciting times with Chubby and ISM.”
Paul joins fellow major winners Danny Willett, Darren Clarke and Louis Oosthuizen, as well as former world No 1 Lee Westwood, at ISM.
Chief cxecutive officer Chandler said: “Paul has been a significant figure on the European Tour for a long time and showed only last week in South Africa what he is still capable of.
“He has done so much in and for golf, he’s a great guy and we’re proud to be working with him.”
ISM will also be representing Paul’s son Craig, who plays on the PGA EuroPro Tour.