Whitehill currently trail Spartans by 24 points and have eight games left, including one against Spartans, and have an inferior goal difference of a massive 38 goals.
It is a tall order for Whitehill but manager Gary Aitchison and his players are not prepared to throw in the towel just yet.
"We know that winning the league will be a hard task but we go into tonight's game with the mentality that we must win," said Aitchison.
"We lost 1-0 to Selkirk on Saturday although we were not out-played in any way. Their goalkeeper had two great saves and ours had very little to do.
"We still have a squad of players who are capable of winning all of our remaining games.
"I need my players to show real desire and heart. I've had a chat with them and they know what I expect."
Whitehill will give a late fitness test to captain Ross Johnston while striker Paul Lynch is unavailable.
Last night, in the Central Taxis Premier Division, Tynecastle drew 1-1 with Civil Service Strollers while in the First Division, Vale of Leithen beat Gala Fairydean 1-0 away from home with a late goal from Alex Munro.
In the British Universities Four Nations Tournament, Scotland overcame Northern Ireland 3-1 while England drew 2-2 with Wales.