The two-vehicle collision on the A97 Kildrummy to Mossat road near Alford at around 12.25pm on Tuesday.
It involved a black Mazda car and a black Kawasaki motorbike.
Police Scotland confirmed the 53-year-old biker died at the scene.
Sergeant Peter Henderson said: "Our thoughts at this difficult time are with the man's family and we have officers supporting them.
"Enquiries into the collision are ongoing and I would urge anyone who was on the A97 or the A944 prior to the time of the collision to contact us."