Motorists using the A87 have been warned to expect delays as there are no suitable alternative routes.
The accident happened at around 10.30am today a mile north of Broadford. the woman’s condition is not yet known.
A Police Scotland spokeswoman said: “Emergency services are in attendance at a serious road traffic collision on the A87, approximately one mile north of Broadford on the Isle of Skye.
“Heli-med is attending for an injured female. One vehicle is involved and the road is closed.”