The accident happened shortly after 4pm yesterday on the B954 Meigle to Dundee road, near its junction with Auchterhouse, and involved an MZ motorcycle and a silver Ford Focus.
A spokesman for the Tayside Division of Police Scotland said: “A trauma unit from Ninewells attended and the 35 year-old female motorcyclist was conveyed to Ninewells hospital Dundee by ambulance, assisted by a police escort, where she is assessed as having head, pelvic and lower limb injuries. Her injuries are described as critical.
“The 66-year-old male driver of the Ford Focus and a 74-year-old male passenger were not injured.”
The road was closed for almost five hours to allow crash investigation enquiries to be carried at the scene. The force spokesman said: “Police officers involved in the investigation are keen to hear from anyone who may have witnessed the incident.”