Julie Reilly, 47, was last captured on CCTV at 5pm on February 6 in an Aldi supermarket in Paisley Road West, Govan.
Detectives and uniformed officers carried out inquiries in Shieldhall Road on Thursday morning.
Officers also boarded buses in the area between 9am and 11am.
Ms Reilly was a frequent user of local transport and officers spoke to passengers and handed out leaflets as part of their investigation.
She was reported missing on February 15 when she failed to turn up for some appointments.
Police Scotland has employed its underwater unit, dog branch and specialist search officers as part of their investigation.
Detective Chief Inspector Mark Bell said: “It is imperative that we do everything that we can to find Julie.
“I am hopeful that these operations will help jog people’s memories, reminding them of when they last saw her.
“We know she used local buses a lot and it’s possible some of the people who use these routes regularly may have seen her or spoken to her.
“I’m hoping the information we gather here will yield some positive results enabling us to follow up lines of inquiry which will lead us to locating Julie.
“Understandably, her family are incredibly concerned and just want to know what has happened to her, I would appeal to anyone who has any information about Julie or about where she may have gone to contact us.”
Ms Reilly, who has been known to use the surnames Hanlon, Martin and Collins, is white, around 5ft, with a medium build and dyed blonde short hair.
When last seen she was wearing a pink jacket, jeans and aqua-coloured trainers.
Anyone with information is asked to call 101.