Dr David Pullinger was director of the project in the 1980s and went on to play a leading part in the introduction of electronic publishing before taking up his present role. He will give an address on "Info-technology and the citizen".
The Church set up the SRT project in 1970 to help the church engage constructively with the scientific community both in Scotland and overseas.
Also speaking at the conference in Edinburgh City Chambers will be the project's first director, Dr John Francis, who has also written a history of the project to coincide with the anniversary, and Dr Donald Bruce, who was director in the 1990s.
And the event will be chaired by yet another former director, Professor Howard Davis.