A survey carried out by Cadbury Dairy Milk found that 37% of those questioned thought Roger Rabbit's seductive wife Jessica was the most alluring character.
Betty Boop, famed for her short skirts and curly black hair, was the second favourite with 21% of the votes and the chocolate-loving bunny came in third with 10%.
The trio beat off strong competition from other cartoon beauties such as Cinderella, Wilma Flintstone, Snow White and Daphne from Scooby Doo.
The study of 1000 people was carried out to celebrate the return of the Cadbury bunny to billboard and magazine adverts.
The seductive rabbit first hit our television screens in the 1980s and has since proved a massive hit with the public.
Commenting on the popular bunny, Lee Rolston, marketing director for Cadbury Dairy Milk, said: "The top three are all similar in that they share the most alluring virtues but what we find most impressive is that she is the only British character on the list.
"In this way she very much echoes Cadbury Dairy Milk's British roots."
Of those questioned, 28% said body shape was the most alluring quality in a female cartoon character, while others said large enticing eyes and a memorable voice were important attributes.
Jessica Rabbit's red dress was named as the most recognisable item of clothing worn by a cartoon character, with Snow White's yellow and blue dress coming in second.