The incident happened on the southbound A1 near Torness power station in East Lothian at 11.25am on Tuesday.
One of the HGV overturned and caused a blockage on the lane. The other ended up on the side of the road.
No one was injured in the incident.
As a result of the incident, the southbound route has been closed while emergency services deal with the vehicles.
The road is expected to reopen later this afternoon.
Motorists are being urged to drive with care as warnings for high winds have been put in place for bridges across the country.
The Forth and Skye bridges have been closed to high-sided vehicles.