Edinburgh men needed for male contraceptive study

Men will be asked to use a daily gel that suppresses sperm production as their only method of birth control as part of two-year study to assess if it is effective in preventing pregnancy and whether this method is acceptable to couples.
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The gel – called NES/T – is a hormone-based treatment designed to reduce sperm production without affecting libido.

Men will apply the gel daily to their upper arms and shoulders and attend monthly clinics to monitor sperm count.

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Condoms and vasectomy are currently the only form of contraception available to men. Many women experience unacceptable side effects with their contraceptive method and so couples are looking for alternatives.

The study is being led in the UK by the University of Edinburgh and Saint Mary’s Hospital, part of Manchester University NHS Foundation Trust.

It is part of an international project funded by the US National Institute of Health and led by the Los Angeles Biomedical Research Institute and the University of Washington School of Medicine.

Men aged between 18 and 50, who are in a stable relationship with a woman aged between 18 and 34, are invited to be part of the trial by calling 0131 242 2669 for the Edinburgh study and 0161 276 3296 for the Manchester trial.

Professor Richard Anderson, of the University of Edinburgh’s MRC Centre for Reproductive Health, said that because the gel was applied by the men themselves it cut out the need for time-consuming clinic appointments.

“Previous trials have shown that hormonal contraception for men can be safe and effective.

“This trial allows men to self-administer a gel, which may be much more convenient and acceptable than needing repeated injections, as was the case with previous trials.”

Dr Cheryl Fitzgerald, consultant gynaecologist at Saint Mary’s Hospital, who is leading the study in Manchester said: “Currently the contraceptive options for men are limited to condoms and vasectomies. We believe this preparation will allow men to control their fertility in a safe and simple way.”

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