She will be joined by National Clinical Director Jason Leitch and Police Scotland Chief Constable Iain Livingstone.
Ms Sturgeon will speak at St Andrew's House today to deliver the latest statistics on the Covid-19 pandemic in Scotland.
Coverage will shown on BBC One Scotland from 1.30pm today.
Today's conference comes as her own government criticised the UK government for giving mixed messages over lockdown.
Earlier on Friday, John Swinney attacked the way the UK Government has communicated plans for lockdown easing, saying Prime Minister Boris Johnson has given "entirely the wrong message".
The Deputy First Minister was speaking on the BBC's Good Morning Scotland radio programme on Friday when said he hopes Scotland and the UK can remain in lockstep over lockdown measures.
Mr Swinney branded messages coming from Westminster to English media as "disastrous" and a "foolish mistake to be made".
Yesterday, Ms Sturgeon insisted she would "not be pressured" into lifting the lockdown before she was certain that it was safe to do so.
The First Minister said "any significant easing up of restrictions would be very very risky", adding that the move would only be considered once she was "confident that the all-important R number is comfortably below 1".
A message from the Editor:
Thank you for reading this story on our website. While I have your attention, I also have an important request to make of you.
With the coronavirus lockdown having a major impact on many of our advertisers - and consequently the revenue we receive - we are more reliant than ever on you taking out a digital subscription.
Subscribe to scotsman.com and enjoy unlimited access to Scottish news and information online and on our app. With a digital subscription, you can read more than 5 articles, see fewer ads, enjoy faster load times, and get access to exclusive newsletters and content. Visit https://www.scotsman.com/subscriptions now to sign up.
Our journalism costs money and we rely on advertising, print and digital revenues to help to support them. By supporting us, we are able to support you in providing trusted, fact-checked content for this website.