But Hughes warned his players that the only way they will take all three points from Billy Reid's side on Saturday is to keep their head on the pitch.
The Easter Road side look set to suffer from suspensions in the final weeks of the season with Sol Bamba facing a three-match ban and Liam Miller and Ian Murray on the verge of joining him on the sidelines.
The last time Hibs travelled to Hamilton they lost 2-0, with Colin Nish being sent off in the dying minutes, and Hughes knows that his side can't afford to lose their discipline this time around.
Having seen his side narrowly lose out to Celtic at the weekend, Hughes said: "We have got to get back to winning ways, there is no doubt about it.
"There is disappointment and frustration from the players but there is no point in dwelling on what happened against Celtic, our sole focus and concentration this week must be on Hamilton, Hamilton and Hamilton.
"They are a right good side and I never for a minute thought that they would be in danger of being relegated.
"If we are going to beat them on Saturday then we have to be right at ourselves and keep our heads.
"There have been one or two bits and pieces in the last couple of weeks that I have picked up on that I think we could improve. We've maybe given away penalties or silly fouls, picked up daft bookings and all of these things can come back to bite you, especially in terms of suspensions.
"It's something that I will mention to the boys in the dressing room and make them aware of.
"If we could get back on track and get that European place that would be great for the club."