Jonsson misses Saturday's encounter with Motherwell after being dismissed against Rangers on Sunday, while cautions incurred by Kingston and Obua at Ibrox have pushed them through the SFA's disciplinary points threshold.
They are now excluded from the meeting with Dundee United at Tynecastle on Wednesday 5 May.
"It's disappointing to lose these boys but it's part and parcel of the game," said Jefferies. "These things pile up so we'll have to deal with it just like we have to deal with other suspensions and injuries."
Jefferies opined that Jonsson's ordering off for a professional foul on Rangers' Steven Naismith may not have warranted a red card.
"I thought Eggert's sending off was a bit soft," continued the manager.
"Steven Naismith was very clever and made it difficult for the referee but the one good thing about it is that he hasn't gone through any thresholds and only misses Saturday's game against Motherwell.
"Larry and David also picked up one game and that will be against Dundee United, so everyone will be available for the game against Hibs at Easter Road."