Whitehill defeat at Selkirk all but ends title hopes
Spartans were on League Cup duty and beat Coldstream 1-0 with a Keith McLeod penalty. Edinburgh City defeated Civil Service Strollers 4-3 after extra time.
Michael Dick and James Craigen scored in Edinburgh University's 2-1 victory over Eyemouth United, while Preston Athletic beat Kelso United on penalties after the teams finished 3-3 after extra time.
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Hide AdTynecastle beat Heriot-Watt 3-1, Lothian Thistle overcame Gala Fairydean 7-0 and Leith Athletic scored a staggering 16 goals against Hawick Royal Albert.
In the First Division, Stirling University took over top spot after beating Gretna 2008 1-0 while Vale of Leithen beat Peebles 4-0.