The first match between the arch-rivals will take place on Saturday 21 September at Easter Road, though that match will likely be moved to an earlier kick-off or to the Sunday for live TV broadcast.
The final derby before the split is another midweek contest. Hibs will host Craig Levein's side at Easter Road on Wednesday 4 April.
The two sides will play each other once more in the league if both finish in the top six or bottom six.
Hearts begin their campaign with a trip to Aberdeen. Hibs host St Mirren.