Wright, 41, worked his way up from young all-rounder to World Cup skipper and record cap-holder before taking up a series of backroom roles.
He said: “The time is right to take on new challenges and explore other interests.
“Scottish Cricket has been my passion since I first played as a 13-year-old. I have been incredibly fortunate to have had some wonderful experiences on and off the field since then. I will depart after the forthcoming WT20 tournament in India – an event which gives us another opportunity to prove that we deserve to be on the global stage.”
Cricket Scotland performance director Andy Tennant led the tributes to Wright.
He said: “It is hard to put into words the size of the contribution Craig has made to the game in this country.
“His record as a player and captain speaks for itself – but more important is his incredible work ethic, drive and determination.
“His passion about developing young Scottish players will be his legacy.”
Meanwhile, Scotland outcast Majid Haq is one of just two Scots to be included in the draft for this year’s Hero Caribbean Premier League.
Scotland’s current most capped player and record wicket-taker could join some of the game’s superstars in the West Indies this summer.
The Clydesdale all-rounder is joined by Falkland’s fast bowler and hard-hitting batsman Safyaan Sharif. Both are gunning for a place in one of the six franchises who will contest the biggest CPL yet with the auction taking place on 11 February.
Haq has not played for Scotland since being sent home from last year’s World Cup in Australia for posting a race-related tweet.
He subsequently lost his Cricket Scotland contract but is determined to battle his way back into the international fold.
Sharif is currently with the national squad in Dubai as they continue their preparations for next month’s T20 World Cup.
l Scotland’s U19s completed the group phase of their World Cup with a heavy defeat by South Africa in Bangladesh yesterday.
Arbroath’s Harris Carnegie top-scored with 29 not out as the lower order helped the Scots recover from 92 for eight to reach 127.
However, South Africa’s opening batsmen rattled off the runs to secure a ten-wicket success.
Scotland will face New Zealand in the quarter-final of the Plate tomorrow.