The 27-year-old has struggled all through 2014 to regain peak form and fitness following back surgery almost a year ago.
Form remains a concern to his fans if not seemingly to the man himself, but fitness-wise Murray could scarcely be happier.
The back pain that lingered through the first part of the season is in the past and the Scot had time after Wimbledon to put in some serious work at a training camp in Miami.
Asked when the last time was he felt so well prepared for a Grand Slam event, Murray said: “Australian Open last year, Wimbledon last year would have been the last two.
“Obviously I missed the French. My back was not great during this event last year. This year, this would be the best prepared I have been coming into a slam.
“I got a great training block over in Miami done, so physically I’m where I would want to be.
“My body is pain-free, which is good. I feel ready. I feel confident and I’m looking forward to the start.”
Murray begins his campaign against world No 70 Robin Haase this evening. The Scot is scheduled to play second on Flushing Meadows’ second court, Louis Armstrong, where Murray has had many major struggles in the past, at around 6pm UK time.