From southern England, it will appear in the west at about 4.24pm and remain visible for six minutes before disappearing below the south-eastern horizon.
Viewed from further north, the space station will appear lower in the sky, but should still be visible from the north of Scotland.
On board the space station, British astronaut Major Tim Peake and the rest of the crew will be treated to a spectacular sight as their orbiting craft flies over the “Christmas lights” of European cities and towns after sunset.
Robin Scagell, vice-president of the Society for Popular Astronomy, said: “The space station’s maximum elevation will be about 23 degrees viewed from London, which is just above the rooftops.
“It will be the brightest star in the sky, moving rapidly from west to east. You might think it’s a plane to start with, but you’d hear the engine noise of an aircraft that close and of course the space station is silent.
“So we’ll be able to see a different object flying over the rooftops on Christmas Day.”
A full moon is also due make an appearance on Christmas Day, but it is not due to rise until the International Space Station has completed its journey.