MISLEADING results from poorly conducted animal experiments could be putting clinical trial patients at risk, according to an Edinburgh expert.
An investigation of stroke medicines found a number of cases where pre-clinical work on animals had produced skewed data.
At least one drug caused harm to the trial patients it was later given to.
Dr Malcolm Macleod from Edinburgh University said
: "It's certainly the case that human health in clinical trials would be better served if the animal data were of higher quality."