Hughes started at the BBC as a secretary in 1944, before becoming an announcer with a famed elegant voice.
She appeared on the Light Programme, the Home Service and the Third Programme, now known as Radio 3.
In 1969, following a career break, she returned to Radio 3 until she retired in 1983.
For many years, she was the only female announcer on Radio 3.
In addition to her radio work, Hughes recorded a number of audiobooks, including an autobiography of Margaret Thatcher, the BBC said.
She died on Friday at a nursing home in Winchester, Hampshire, and leaves a daughter, Emma, and two grand-daughters.
Michael Berkeley, the presenter of Private Passions on Radio 3, said Hughes had been an “utterly idiosyncratic voice of Radio 3 for many years”.
Roger Wright, the controller of BBC Radio 3, said: “I was saddened to hear about the death of Patricia Hughes, one of BBC Radio 3’s best-loved voices.
“Her contribution to radio in general and the station in particular was significant – not least her memorable introductions to lunch-time concerts.
“She was much loved by our listeners and her death marks the passing of an era.”