Meghan's figure will be placed alongside showbiz royalty at the London attraction to reflect her "independent celebrity status".
The American former actress now take up a spot next to her A-list wedding guests Tom Hardy, the Beckhams and actress Priyanka Chopra - while Harry will rejoin the rest of the Royal
Family replicas in a different room.
Steve Davies, general manager at Madame Tussauds London, said: "We're always listening to what people have to say about their favourite stars.
"Meghan continues to carve out her own modern take on life as a royal and we want to mirror her independent celebrity status in the attraction.
"It's not necessarily forever - and we're not splitting our loved-up couple. We're just allowing Meghan to mingle in her more-familiar celebrity circle for a while."
It is the first time the waxworks will be separated since they were unveiled before the royal wedding in May last year.