The accident happened in Girvan Road, Turnberry, South Ayrshire, at around 4.50pm yesterday when a grey MG ZR collided with a DAF gritting vehicle.
CONNECT WITH THE SCOTSMAN
• Subscribe to our daily newsletter (requires registration) and get the latest news, sport and business headlines delivered to your inbox every morning
The 17-year-old man driving the car suffered serious head and neck injuries. He was taken to Ayr Hospital for treatment before being transferred to the Southern General in Glasgow where he is said to be in a critical condition.
His passenger, a 17-year-old woman, was also taken to Ayr Hospital but her injuries are not thought to be life threatening.
The driver of the gritter was not injured, police said.
Yellow weather warnings for strong winds, ice and snow have been in force for much of the weekend with gritters sent out to prepare for freezing conditions.
The road was closed while the scene was investigated and officers are appealing for any witnesses to contact them.
Meanwhile, a 30-year-old man is in a serious condition after he had to be cut free from his car which crashed off the M8 and into a tree near Edinburgh.
The single-car accident happened at junction four of the motorway at around 12.30pm today and involved a Honda.
The man was taken to Edinburgh Royal Infirmary for treatment and police are appealing for any witnesses to contact them.
SCOTSMAN TABLET AND IPHONE APPS