The former Scruffy Murphy's pub on Melville Place will undergo a full refit to become the Slainte Mhath.
Decorations will include traditional flaming lanterns outside the bar, and a "rustic" interior with wooden tables and traditional fittings. The bar will serve classic Scottish fare, and there are also plans to have a separate area to host live folk music.
Manager Daley Connor said the he wanted to re-invent the pub from its previous well-known incarnation, and hoped the bar would capture some of the spirit of the traditional local.
"We wanted to make it a good old-style pub, so we've gone for a very rustic look, and hopefully that will appeal to a lot of people," he said.
"We'll be looking to put on traditional Scottish folk music as well, in a separate area so that if people want music they can enjoy it."
The Randoph Bar will close on Monday, November 15, and it is hoped the Slainte Mhath will open for business by December 10.