Kirsty Jones, 41, died from the killer bug on April 20.
She had two young sons, Finlay, aged four, and Sam, 14, as well as widower Nigel.
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Hide AdThe dedicated NHS worker started her career aged 17, and colleagues applauded a hearse as it passed by University Hospital Wishaw in Lanarkshire, where she worked.
The guard of honour was organised at the request of the family, as so few people could attend the funeral given current restrictions on public gatherings.
Anne Leitch, chief of nursing services at University Hospital Wishaw, said: "This was a very fitting tribute to a much loved colleague and friend.
"It gave staff the chance to pay their last respects and showed the family how highly regarded Kirsty was."
Staff from the hospital and other emergency services lined the main road in the hospital grounds to clap their hands as the procession passed by.
Anne added: "From everyone at the hospital, and across NHS Lanarkshire, I would like to extend our sincere condolences to Kirsty's family."