A coach left the carriageway heading southbound on the A1 near the QMU junction, however no passengers were on board.
A driver has since been taken to hospital to receive treatment.
The incident took place at 7:55am with emergency services attending.
There was another accident heading northbound on the A1 at junction A199 involving 4-5 vehicles.
It is thought that no one was seriously injured during the incident however officers are currently at the scene.
A section of the A1 between Newcraighall and Old Craighall had been closed but has since reopened.