A woman has been left in a serious condition and three others injured after a two-car collision.
The incident happened at around 6.45pm on Saturday near Moffat in Dumfries and Galloway.
An Audi A5 travelling south towards Dumfries collided with a northbound Volkswagen Golf on the A701.
The 55-year-old male driver of the Audi and his 57-year-old female passenger sustained serious injuries.
The 25-year-old male driver of the VW and his female passenger, 20, were also injured.
All four were taken to Dumfries and Galloway Royal Infirmary and remain there for treatment.
Medical staff describe the condition of the 57-year-old woman as serious.
Sergeant Paul Dodds said: “The A701 is one of the main roads which connects the M74 to Dumfries.
“A number of people stopped to assist the injured parties, however, we are still keen to speak to anyone who may have not yet come forward to police, who may for example have dashcam footage, or who saw the cars just prior to the crash.”