Tom Toumazis, currently chief commercial officer at Endemol, will become chief executive in August, replacing David Montgomery, who stood down in January.
Stephen Davidson, currently executive chairman, becomes non-executive chairman when Toumazis joins the firm.
Mecom owns more than 300 printed titles and more than 200 websites in its four divisions with operations in the Netherlands, Denmark, Norway and Poland.
Toumazis said: "It has considerable potential to develop its multi-media platforms and build strong digital revenues and I am excited to be given the opportunity to lead the company."
Toumazis is also chairman of the charity ChildLine.