Research discovers molecule that can switch off cancer

Published on Thursday 11 March 2010 21:35

SCIENTISTS have found a "switch" that can turn off cancer without the side effects of chemotherapy.

Researchers have found a molecule that actually triggers cell death, and they are confident it can be developed into a treatment for cancer and other illnesses.

They found that the molecule called caspase, which was already well known for killing cells, could be used to target specific cancerous ones.

If the finding can be turned into a treatment it would be a dramatic improvement on chemotherapy which kills healthy cells and well as the cancerous cells to treat the disease.

The study, from the University of Colorado, was published in the 12 March issue of Science. Professor Ding Xue, who led the five-year study, said: "Our findings initially seemed too good to be true.

"We wound up looking at the results from a number of angles, including genetics, cell biology and biochemistry.

"Eventually we reached the only logical conclusions we could make."

He added: "This is a completely novel finding, and all of the players in this story are well-known, well studied aspects of a very important process in our lives.

"The minute I saw the results, I knew it was a very, very important finding with wide implications."

The experiments were undertaken on a common, eyelash-sized nematode known as Caenorhabditis elegans, a popular laboratory organism for genetic and biomedical experiments.