Laser beams to help detect cancer of the bladder

Published on 03/10/2012 02:18

A NEW technique using laser beams could help detect bladder cancer, scientists have said.

Researchers said that the technique, called “Raman spectroscopy” (RS), which involves shining a light beam on to a sample of tissue to reveal any abnormalities, could be quicker and more reliable than the current biopsy method.

Diagnosis could be made 
almost instantly while biopsy results can take up to two weeks, they said.

The scientists, from the University of Dundee, examined 14 patients at Ninewells Hospital who presented with symptoms of bladder cancer.

Their study, published in Analytical and Biological Chemistry, found that diagnosis made using RS was consistent with the biopsy results in 13 cases.

Dr Ghulam Nabi, lead researcher, suggested that RS has potential to be used to make less-invasive and quicker diagnoses. He said: “Obviously, the earlier we diagnose cancer, the better the prognosis is for the patient.

“There are some specific difficulties in making a reliable early diagnosis of bladder cancer, and very often it is not diagnosed until the cancer has manifested itself as a variety of symptoms.

“What we have been looking to do is develop an early and reliable diagnosis of urinary bladder cancer. Raman spectroscopy tells us about technical structure of tissue before morphological changes in structure happen as a result of the cancer developing.”

Dr Nabi said patients and their families faced an anxious wait for results with the current procedure, and he stressed 
that the RS can provide a quick diagnosis.

He added: “What we need to do now is expand our study population and refine the process until it is as reliable as 
biopsy, but without the negative 
side-effects.”