Jonny Wilkinson to face Falcons in Amlin
Championship winners Worcester's return to European competition pits them alongside last season's beaten finalists Stade Francais, Crociati Parma and Bucharest Wolves in pool one.
The five pool winners advance to the quarter-finals, where they will be joined by three pool runners-up from the Heineken Cup, the final will be played on the weekend of 18/19/20 May.
2011/12 Amlin Challenge Cup
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Hide AdPool One: Stade Francais Paris, Worcester Warriors, Crociati Parma, Bucharest Wolves.
Pool Two: Toulon, Newcastle Falcons, Petrarca Padova, Lyon Rugby.
Pool Three: London Wasps, Bayonne, Femi-CZ Rovigo, Bordeaux-Begles.
Pool Four: Perpignan, Newport Gwent Dragons, Exeter Chiefs, Cavalieri Prato.
Pool Five: Sale Sharks, Brive, Agen, Club de Rugby La Vila.